Over the eons, mice have gained dpi, and they have also gained buttons. Most people use mouse1 for fire, and mouse2 for alternate fire. The question is, should mice have more buttons, and should people use the buttons on a mouse to fire, or should the buttons even exist?

There is a school of thought suggesting that the best way to aim is to not use or have buttons on a mouse. The hypothesis is that if pressing or holding one of the mouse buttons leads to improved aim, regardless of whether the button has any actual function, the person would still press or hold it. Therefore, the way to achieve highest aim, is to unbind all buttons from the mouse, or to simply have no buttons whatsoever.

To my knowledge, there is no mouse without buttons. If one were to be created, it is possible the mouse would be more effective for aiming or other precision functions than the typical mouse of today. The shape, weight and sensor would be the focus, as opposed to the number or positioning of buttons.

Of course, it's hard to bind all the things you need without mouse-buttons, but that's a separate issue.